Effectiveness of cefotaxime in preventing surgical site infections in children under 8 years undergoing elective inguinal surgery at the university teaching hospitals, Lusaka, Zambia
| dc.contributor.author | Patel, Azad | |
| dc.date.accessioned | 2022-05-20T14:08:30Z | |
| dc.date.available | 2022-05-20T14:08:30Z | |
| dc.date.issued | 2021 | |
| dc.description | Thesis | en |
| dc.description.abstract | Inguinal operations are the most commonly performed surgeries in children. There is a divergent view on use of pre-operative antibiotic prophylaxis to prevent surgical site infections (SSI) after these surgeries. The aim of this study was to detect if the use of cefotaxime had a significant impact on prevention of SSI in children under 8 years undergoing elective inguinal surgery at the University Teaching Hospitals, Lusaka. This was a cohort study. A total of 170 patients below 8 years of age undergoing elective inguinal herniotomy, orchidopexy or patent processus vaginalis (PPV) ligation at UTHs were enrolled. 85 of these received pre-operative cefotaxime while 85 did not receive any antibiotics based on surgeons preference. A data collection sheet was used to record pre-operative demographic details. Intraoperative variables and post-operative outcomes. No patient received post-operative antibiotics. Follow up to look for Surgical site infection was done at 2 weeks and 30 days according to Center for Disease Control (CDC) definition of SSI. Out of 170 patients, 11(6.47%) had SSI. Six of the 85 that received surgical antibiotic prophylaxis (SAP) had SSI while 5 of the 85 that did not receive SAP had SSI (P=0.551). Deep SSI were seen in 2 patients that did not receive SAP (p=0.155) and grew Staphylococcus aureus in their cultures. Only 1 adverse allergic reaction to preoperative antibiotics was noted. Despite a low risk of adverse reactions, there is no benefit of using pre-operative antibiotics to prevent SSI in children undergoing elective inguinal surgery. Keywords: Surgical site infections, Surgical antibiotic prophylaxis, Inguinal surgery, PPV ligation, Herniotomy, Orchidopexy | en |
| dc.identifier.uri | http://dspace.unza.zm/handle/123456789/7324 | |
| dc.language.iso | en | en |
| dc.publisher | The University of Zambia | en |
| dc.subject | Surgical site infections. | en |
| dc.subject | Surgery, Operative--Handbooks, manuals, etc. | en |
| dc.subject | Inguinal lymphadenectomy. | en |
| dc.subject | Inguinal surgery. | en |
| dc.title | Effectiveness of cefotaxime in preventing surgical site infections in children under 8 years undergoing elective inguinal surgery at the university teaching hospitals, Lusaka, Zambia | en |
| dc.type | Thesis | en |