• Login
    View Item 
    •   UNZA Repository Home
    • Theses and Dissertations
    • Veterinary Medicine
    • View Item
    •   UNZA Repository Home
    • Theses and Dissertations
    • Veterinary Medicine
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Toxicity testing of SIDA cordifolia(Flannel weed) in goats in Zambia

    Thumbnail
    View/Open
    jembe0001.PDF (10.01Mb)
    Date
    2012-09-05
    Author
    Jembe, Josias
    Type
    Thesis
    Language
    en
    Metadata
    Show full item record

    Abstract
    Sida cordifolia, family Malvaceae, was suspected to have caused toxicity in small ruminants (sheep and goats) at one of the farms around Lusaka. To verify the suspicion the present study was planned and undertaken. The study included (a) experimental feeding of female goats with Sida cordifolia (b) retrospective study of liver and kidney specimens from the affected farm as well as neighboring farms with suspected plant poisoning and (c) a questionnaire survey on the same farms to gather information on farm management, animal husbandry, vegetation and disease outbreaks in case there were other agents responsible for the out break at the affected farm. Three toxicity tests were conducted using 14 healthy female goats aged between 8 to 18 month and weighing 12 to 18kg body weight. The goats, all from one herd, were let to acclimatize for two weeks in a room with a concrete floor. During this period, the animals were clinically examined and deworrned. The plant used in the toxicity test was picked at flowering stage; and only tender aerial leaves together with flowers and seeds were dried in the shade, milled and stored at -10°C. The first experiment involved five goats. Two of the goats were drenched at a dosage of 5g (dry matter; D.M.)/kg body weight and another two received a dosage of lOg (D.M.)/kg body weight. One goat was used control. The goats were dosed for 5 consecutive days and observed for 10 days. The second toxicity test comprised six goats but only two completed the course having been drenched with lOg (D.M.)/kg of the milled plant material for 10 consecutive days and observed for 30 days. The third and final test involved three goats but only one completed the experiment on a dosage of 5g (D.M.)/kg for 20 consecutive days and observed for 20 days. Rectal temperature, respiratory rate, heart rate, pulse rate, and rumen motility were measured during the experiments. Signs of jaundice and photosensitivity were monitored. Serum metabolite indices known to be sensitive indicators of liver damage, gamma-glutamyltranspeptidase (GOT) and aspartate
    URI
    http://dspace.unza.zm/handle/123456789/1739
    Subject
    Veterinary plant toxicology-Flannel Weed in Goats
    Collections
    • Veterinary Medicine [87]

    DSpace software copyright © 2002-2016  DuraSpace
    UNZA homepage | UNZA Library | Contact Us | Send Feedback
    Theme by 
    Atmire NV
     

     

    Browse

    All of UNZA RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    View Usage Statistics

    DSpace software copyright © 2002-2016  DuraSpace
    UNZA homepage | UNZA Library | Contact Us | Send Feedback
    Theme by 
    Atmire NV