A case series report of Tuberculosis patients with Vitamin D deficiency in Zambia
Date
2018-01
Authors
Lungu, P.
Lakhi, S.
Mateyo, K.
Mubiana, E.
Mwaba, P.
Journal Title
Journal ISSN
Volume Title
Publisher
Medical Journal of Zambia.
Abstract
An association of Vitamin D deficiency with Tuberculosis remains a valid assumption. It has been observed that TB is highly prevalent in certain ethnic groupings and regions of the world. Populations with darker skins are prone to vitamin D deficiency. The regions inhabited by people with darker skin coincides with high TB burden settings. Vitamin D has a key role in immune-modulation of the host response to Mycobacterium Tuberculosis infection. Studies have demonstrated early sputum culture conversion to negative, clinical recovery and radiological improvement with Vitamin D supplementation. However, there is currently no consensus on the advantages of this supplementation in TB treatment. We present the first case series report of pulmonary TB patients with severe deficiency of Vitamin D in Zambia. Additional data from randomised control studies is warranted.
Description
An association of Vitamin D deficiency with Tuberculosis
Keywords
Tuberculosis--Zambia , Tuberculosis, Vitamin D Deficiency--Zambia , Vitamin D Deficiency--Zambia
Citation
Lungu, S., Lakhi, K., Mateyo, E., Mubiana and Mwaba, P. (2018). A case series report of Tuberculosis patients with Vitamin D deficiency in Zambia. Medical Journal of Zambia. 45 (1)