This research paper contains a study carried out at serenje technical high school in the performance of female pupils in physical science academic production unit (APU). The researcher used question and an observation schedule to collect data from teachers and pupils in order to arrive at the findings. Part of the data was converted into table forms and graphs while part of it was Analysed qualitatively and quantitatively. Results indicate that, female pupils can perform better in physical science subjects if only they are encouraged by teachers and parents.