This study assesses the impact of climate change on water resources in the Lwitikila River, located in Mpika District of Northern Zambia. The main aim of this study was to find out the impact of climate change on water resources in the Lwitikila River. The study analyses the effects that temperature, sunshine hours and rainfall variations have on discharge and water level measurements and further assesses the local people's response and adaptability strategies to the effects of climate change.