A descriptive study of outcomes of interventions to prevent mother to child transmission of HIV in two primary health care centres in Lusaka, Zambia
| dc.contributor.author | Sichitamba, Chibesa | |
| dc.date.accessioned | 2013-04-15T09:27:29Z | |
| dc.date.available | 2013-04-15T09:27:29Z | |
| dc.date.issued | 2013-04-15 | |
| dc.description.abstract | Background:Mother-to-child transmission (MTCT) of HIV still remains a major problem worldwide accounting for 90% of the infection in children under the age of fifteen years. In Zambia, Prevention of Mother to Child Transmission (PMTCT) of HIV activities have been carried out for over a decade. Few studies have described the outcome of the interventions. This study, a retrospective observational cohort study, determined whether the PMTCT interventions have been of benefit to HIV exposed children, by reducing HIV vertical transmission.Method:Data was extracted from the clinical and laboratory records of 534 mother-infant pairs in the MTCT-Plus cohort. Analysis using Pearson Chi –square test for categorical variables, and bivariate and multivariate regression analysis to examine predictors of a positive HIV outcome was done.Results:A total of 534 infants had their final HIV status established, of which 101 (18.9%) were positive.The proportion of infants with a positive HIV test was much lower in infants where the maternal regimen was Highly Active Antiretroviral Therapy (HAART) at 6.6% (6/91), whilst that of infants where the maternal regimen was single dose nevirapine was 19.9% (74/372).Conclusion: This study indicates that the Prevention of Mother-to- Child | en_US |
| dc.identifier.uri | http://dspace.unza.zm/handle/123456789/2219 | |
| dc.language.iso | en | en_US |
| dc.subject | Virus disease-Transmission | en_US |
| dc.subject | Virus disease in pregnancy | en_US |
| dc.subject | HIV/AIDS in Women | en_US |
| dc.title | A descriptive study of outcomes of interventions to prevent mother to child transmission of HIV in two primary health care centres in Lusaka, Zambia | en_US |
| dc.type | Other | en_US |