Factors influencing non-adeherence to tuberculosis treatment in TB/HIV co-infected adults at the University Teaching Hospital,Lusaka,Zambia
| dc.contributor.author | Ramadhani, Asha | |
| dc.date.accessioned | 2018-07-11T09:23:31Z | |
| dc.date.available | 2018-07-11T09:23:31Z | |
| dc.date.issued | 2017 | |
| dc.description | THESIS MSC (EPIDEMIOLOGY) | en |
| dc.description.abstract | Zambia is a high TB/HIV prevalence country. The aim of this study was to explore barriers to TB treatment adherence and determine the prevalence of non-adherence in the Zambian capital of Lusaka. The factors under study were socio-economic and demographic, service-related and disease and treatment related factors. A cross-sectional study was conducted on 239 TB patients co-infected with HIV, using an interviewer-administered structured questionnaire. Chi-square test was used for bivariate analysis of the outcome and independent variables. Logistic regression was used to obtain the best model because the study had a binary outcome. The prevalence of non-adherence was found to be 8.4%. Factors that influenced adherence to TB treatment were response to treatment (p=0.038) and the affordability of transport costs (p<0.001) to the health-care facilities. The odds of a patient defaulting treatment due to their response to the TB drugs were up to 17 times higher for those with a poor response than those of a patient with an average response. This study found a low level of non-adherence to TB treatment. Economic constraints and treatment factors pose a threat of non-adherence to TB treatment. Social support and intensive counseling might help to mitigate this threat. Further studies addressing sensitization, intervention and their impact assessment are recommended. Keywords: Tuberculosis, HIV/AIDS, Non-adherence, co-infection | en |
| dc.identifier.uri | http://dspace.unza.zm/handle/123456789/5240 | |
| dc.language.iso | en | en |
| dc.publisher | The University of Zambia | en |
| dc.subject | TB/HIV--Treatment--Zambia | en |
| dc.subject | TB/HIV--Adherence--Zambia | en |
| dc.title | Factors influencing non-adeherence to tuberculosis treatment in TB/HIV co-infected adults at the University Teaching Hospital,Lusaka,Zambia | en |
| dc.type | Thesis | en |