Raised Levels: A Risk Factor for Cardiovascular Associated Complications in HIV Positive Zambians before Initiation of Antiretroviral Therapy
| dc.contributor.author | Mantina, F.H. | |
| dc.contributor.author | Mwaba, F. | |
| dc.contributor.author | Sinkala, M. | |
| dc.contributor.author | Kwenda, G. | |
| dc.contributor.author | Kaile, T. | |
| dc.contributor.author | Nhhoma, P. | |
| dc.date.accessioned | 2018-07-09T14:55:51Z | |
| dc.date.available | 2018-07-09T14:55:51Z | |
| dc.date.issued | 2017 | |
| dc.description | Plasma levels of IL-6 in HIV positive and HIV negative individuals and to correlated with CD4 count | en |
| dc.description.abstract | The objectives of the study were to compare plasma levels of IL-6 in HIV positive and HIV negative individuals and to correlate them with CD4 count Materials and methods: A cross-sectional study was carried out at the University Teaching Hospital in Lusaka, Zambia. IL-6 and CD4 were assessed in HIV positive on ART, HIV positive ART- naïve and HIV negative control participants. Results and Conclusion: Our study showed that HIV ART naïve participants had higher IL-6 concentrations (2.83 ± 1.60 ng/ml) than those on ART (2.49 ± 1.21 ng/ml) p = 0.020. HIV negative control participants however, had higher concentrations of IL-6 (3.24 ± 1.33 ng/ml) than HIV positive participants on ART (2.49 ± 1.21) p = 0.002. HIV positive ART naïve individuals therefore, had the highest IL-6 levels. The results also showed that ART lowers inflammation in HIV and this may explain why ART reduces the risk of developing opportunistic tumours and other infections in HIV . | en |
| dc.description.sponsorship | Office of Global AIDS/US Department of State. | en |
| dc.identifier.citation | Mantina, F.H., Mwaba, F., Sinkala, M., Kwenda, G., Kaile, T. and Nhhoma, P. (2017). Raised Levels: A Risk Factor for Cardiovascular Associated Complications in HIV Positive Zambians before Initiation of Antiretroviral Therapy. Medical Journal of Zambia. 44 (2) | en |
| dc.identifier.uri | http://dspace.unza.zm/handle/123456789/5223 | |
| dc.language.iso | en_US | en |
| dc.publisher | University of Zambia, Medical Library | en |
| dc.relation.ispartofseries | Medical Journal of Zambia. 44 (2); | |
| dc.subject | HIV Seropositivity | en |
| dc.subject | Cardiovascular Diseases | en |
| dc.subject | HIV Infections--Zambia | en |
| dc.subject | Heart Diseases--HIV Infections--Zambia | en |
| dc.title | Raised Levels: A Risk Factor for Cardiovascular Associated Complications in HIV Positive Zambians before Initiation of Antiretroviral Therapy | en |
| dc.type | Article | en |