Calcinosis circumscripta in a captive African cheetah (Acinonyx jubatus)
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Date
2014
Authors
Mumba, Chisoni
Squarre, David
Mwase, Maxwel
Yabe, John
Shibahara, Tomoyuki
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Calcinosis circumscripta is an uncommon syndrome
of ectopic mineralization characterized by deposition of
calcium salts in soft tissues. It has been thought to be
associated with cystic apocrine glands of the skin, and
some researchers called this lesion ‘‘cystic apocrine
calcinosis’’[1]. However, calcinosis circumscripta has been
found in the tongue, which lacks apocrine glands[1]. The
focal mineralized lesions are most frequently located in the
region of extremity joints as well as cervical and thoracic
spine segments[2]. The other sites predisposed to develop
such pathological changes, with very few references in the
literature, may include the mouth, gingiva, frenulum of the
tongue, salivary glands, pinna, mandible, chest region and
jejunum[2].
Dystrophic calcinosis circumscripta occurs when the
serum calcium and phosphate levels are normal and
the calcification is localized to a specific area of tissue
damage. The primary lesion can be due to injury, necrosis,
inflammation or neoplasia. Tissue damage may be due
to mechanical, chemical, infectious or other factors[3].
Calcinosis circumscripta has not previously been reported
in a cheetah, hence necessitating the publication of this article
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Description
Journal article
Keywords
Calcinosis circumscripta, , von Kossa, , Cheetah, Zambia